Rubber latex is, by its very nature, a natural substance. The natural rubber latex polymer used in the manufacture of natural rubber gloves is a biodegradable material that is inherently antimicrobial and antibacterial. The 5048 features 15 mil thickness medical grade (Class 1 medical device), textured grip and is powder free. !! CAUTION !! These products contain natural rubber latex which may cause allergic reactions in some people.